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ASINA

Anticipating Safety Issues at the Design Stage of NAno Product Development

Co-Financiado por: -Co-Financiado por

Although previous EU funded projects have defined tools and concepts to ensure safety of nano-enabled products through design, many hurdles still hinder the implementation of these procedures in real production processes. ASINA will use the production value chains (VCs) of two representative categories of nano-enabled products (NEPs): coatings in environmental (clean) nanotechnology and nano-encapsulating systems in cosmetics, to formulate design hypothesis and make design decisions by applying a data-driven approach and methodology (the “ASINA-SMM”).

Molded on industrial six sigma practices, the ASINA-SMM can be easily adopted by manufactures to deliver NEPs designed to be as safe as possible, so achieving ASINA vision to increase stakeholders (entrepreneurs, scientists, regulators, innovators, policy makers, consumers) confidence in SbD nanomanufacturing. The methodology encompasses distinct phases that ASINA will follow to deliver SbD solutions and supporting tools, at TRL6: define NEP, its intended use, production technologies and known quality, safety and cost requirements; measure performance attributes (techno-economic features, hazard and exposure potential along the entire life cycle) in relation to material (M) and process (P) design options; analyse data gathered from internal and external sources and derive/combine response functions, to identify the best compromise between possible design options; design new versions of the product/process that minimise risk, maximising performance; establish a pilot action to verify the capacity of ASINA-SMM to deliver practical, relevant, reliable and reproducible M- or P-SbD solutions.

The project is focused on NEPs that are able to eliminate/contain environmental pollutants (biofilms, bacteria, VOCs) and transport beneficial functions for treating, preventing and healing disease and beautifying the skin. By its end, ASINA will provide a roadmap to generalise ASINA-SMM, and maximizing the positive impacts of further products, designed to improve environmental quality and human health/wellness, offering the transparency required to promote consumer acceptance and, as a consequence, the growth of reference industrial sectors.

The Safe-by-Design concept (SbD) incorporates safety of nano-enabled product (NEP) at the design stage of the production process.

Website: Asina Project

Main goals

1. to support the fast industrial uptake of nanotechnology by providing SbD solutions and supporting tools;

2. to give entrepreneurs knowledge and awareness of SbD potential;

3. to increase confidence in SbD nanomanufacturing by improving the interaction and integration of different stakeholders (entrepreneurs, scientists, regulators, innovators, policy makers).

 

ASINA will develop a specific SbD Management Methodology (the “ASINA-SMM”), consistent with modern business management systems, to deliver SbD solutions and inform design decisions. ASINA will combine and integrate nano-safety characterizing tools and data to provide the science-based criteria for the evaluation of SbD solutions. ASINA will finally export the methodology to the industry through a roadmap (including guidelines, analytical tools, best practices) and other standardization deliverables such as CEN-CWA, as a realistic way to ensure diffusion of the ASINA-SMM and its industrial implementation worldwide.

ASINA has the ambition to promote consistent, applicable and scientifically sound SbD nano-practices, by considering all the NEPs design dimensions: functionality, production technologies, safety, environmental sustainability, cost effectiveness and regulatory requirements, in line with research responsible innovation (RRI) policy.

-Main Goals

Project Number: 862444

Project Duration: March 2020 to August 2023

Eligible Cost: 5,998,386.06 €

Financial support from ERDF: 5,998,386.06 €

Intervention Region: Europe

Type of Action: Research and Innovation Action

Promotor: Consiglio Nazionale delle Ricerche (CNR)

Results


ASINA will have profound impacts on nanotechnology development within industrial innovation, but also on industry competitiveness, on society, on human health and the environment. Successful implementation of ASINA-SMM will help commercializing better and safer products for people.

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